BEAUTY DOSSIER

Natural “Botox-Like” Active Ingredients

Les Actifs “Botox Like” Naturels

ANTI-AGING TREASURES OFFERED BY NATURE


Nature offers an extraordinary wealth of anti-aging actives, from powerful botanical ingredients to natural alternatives to botox, along with essential nutrients. In this complete guide, discover all the actives that slow aging, both topical (to apply to the skin) and dietary supplements (working from within). An IN & OUT approach for optimal results.

TOPICAL BOTANICAL ACTIVES


HORSETAIL

Did you know that horsetail is one of the oldest plants on the planet, having existed on Earth for more than 400 million years? This primitive plant is a true treasure for the skin thanks to its exceptional richness in silica, a mineral essential for collagen production. Horsetail naturally stimulates collagen synthesis by enabling the skin to produce it itself, rather than simply providing it from the outside. This unique action makes it a powerful anti-aging active that restores elasticity and firmness to mature skin. Beyond its effect on collagen, horsetail has remineralizing and regenerative properties that help restructure skin tissues weakened by time. It is particularly effective in preventing skin sagging and maintaining skin tone. Used regularly, horsetail helps smooth fine lines, firm the facial contours, and restore the skin’s natural bounce. Its high antioxidant content also protects the skin from external aggressors and oxidative stress. It is suitable for all skin types, particularly mature skin seeking firmness.

Kakadu Beauty Oil - RMS BEAUTY

Complexe De Fleur - Anti-Aging Serum - IN FIORE

TREMELLA

Tremella is nicknamed “the beauty mushroom” in Asia, where it has been used for centuries by women of the Chinese imperial court to preserve their youth. This translucent gelatinous mushroom has exceptional hydrating power, comparable to or even greater than that of hyaluronic acid. Tremella can retain up to 500 times its weight in water, making it a true natural sponge for the skin. Rich in polysaccharides, antioxidant trace elements, and vitamin D, it protects the skin from premature aging while accelerating cell renewal. Tremella forms a hydrating film on the surface of the skin that locks in moisture and maintains lasting hydration throughout the day. It visibly improves skin elasticity, plumps the features, and smooths dehydration lines. Its anti-inflammatory properties also soothe sensitive and reactive skin. Its lightweight texture absorbs quickly without leaving a sticky finish. It is suitable for all skin types, especially dehydrated and mature skin.

• Holi (Soleil) Firming and Plumping Mineral Sunscreen SPF 50

GOTU KOLA (centella asiatica)

This ancestral medicinal plant, used for more than 3,000 years in Ayurvedic and Chinese medicine, is recognized as one of the most powerful natural skin regenerators. Gotu Kola contains unique actives called saponins (asiaticoside, madecassoside) that directly stimulate the synthesis of collagen and elastin, the two proteins essential for the skin’s firmness and elasticity. These compounds also help repair damaged tissues and promote healing. Gotu Kola helps firm the skin, improve its tone, and maintain stable levels of hyaluronic acid in the tissues. It boosts skin microcirculation, which brings more oxygen and nutrients to the cells and gives the complexion a fresh, radiant look. Its antioxidant properties protect the skin against free radicals responsible for premature aging. Gotu Kola is also soothing and anti-inflammatory, making it a valuable ally for sensitive and reactive skin. It is suitable for all skin types, especially mature, slack, or marked skin.

WILD ROSE OIL

This precious oil, extracted from the seeds of the wild rose bush (Rosa rubiginosa), has been recognized for centuries for its exceptional anti-aging properties. Nicknamed the “oil of youth,” it is exceptionally rich in natural vitamin A (plant-based retinol) and essential fatty acids that intensely stimulate cell renewal and collagen production. Wild rose oil helps visibly reduce the appearance of wrinkles and fine lines, firm the skin, and restore its natural elasticity. Its powerful regenerative properties make it a reference anti-aging active for smoothing facial features, improving skin firmness, and softening the signs of aging. It evens out the complexion, fades age-related pigmentation spots, and restores youthful radiance to the skin. Its richness in antioxidants (vitamin E, carotenoids) protects cells from oxidative stress responsible for premature aging. Wild rose oil also promotes healing and helps repair skin tissues damaged over time. Its dry texture absorbs quickly for deep action without a greasy effect. It is particularly suitable for mature skin, skin marked by time, lacking firmness, or showing wrinkles, fine lines, and pigmentation spots.

Night Repair Elixir - GRESSA SKIN

FRANKINCENSE (Boswellia)

This sacred resin, extracted from the Boswellia tree, has been used for millennia in spiritual rituals and traditional medicine practices for its exceptional therapeutic properties. In modern cosmetology, frankincense is recognized as a powerful anti-aging active thanks to its remarkable regenerative and anti-inflammatory properties. It contains boswellic acids that stimulate cell renewal and promote the repair of skin tissues damaged by time. Frankincense helps firm the skin, reduce the appearance of fine lines, and improve skin texture by stimulating the production of collagen and elastin. Its powerful soothing properties make it an ideal ingredient to calm inflammation, reduce redness, and soothe sensitive or irritated skin. Frankincense also promotes healing and helps fade blemishes and marks left by acne. Its captivating and comforting scent also brings a unique sensory dimension to the skincare products that contain it. It is particularly suitable for mature, sensitive, reactive, or time-marked skin.

Modern Alchemist - Gentlerist

IMMORTELLE (Helichrysum)

Did you know that Helichrysum is called “immortelle” or “everlasting flower” because it does not wilt after being picked from the plant?

It is therefore no surprise that this flower and its essential oil are among the best natural anti-aging ingredients that promote cell renewal.

The Immortelle flower or Helichrysum is used in cosmetology to naturally fight skin aging. In the form of essential oil extracts or floral water, it stimulates collagen production, thereby improving skin firmness. It increases skin microcirculation to promote cell renewal and is used on the body, hands, and face.

This flower, which belongs to the daisy family, has played an important role in traditional medicine for centuries and is revered for its many beauty and skin health benefits.

Highly antioxidant, it helps reduce wrinkles and keep the skin hydrated. It is also antibacterial, making it perfect for acne-prone skin. It boosts radiance and gives tired skin an energizing effect. Its texture is fine, absorbs very quickly, and leaves no greasy residue. It is suitable for all skin types.

Brilliance Face Serum - SOAPWALLA

Jena, founder of the AGENT NATEUR brand, talks to us about her use of helichrysum in the formulation of one of her favorite products:

Holi (Oil) is an anti-aging face oil that refines skin texture. It is one of the first products I formulated, when I had just started studying at my natural cosmetics and perfumery school in Grasse, France. This product is one I am most proud of. Filled with Helichrysum, Rosehip (a natural retinol), and vitamin A, this refined oil combines the highest quality natural, organic, or wildcrafted ingredients.

"I love this immortal flower because when I use it on my face or body, I feel like it regenerates and nourishes my skin at the cellular level."

Jena Covello - Founder of AGENT NATEUR

Thanks to its antioxidant, antibacterial, and anti-inflammatory power, Helichrysum extract can not only help fight psoriasis, but also skin conditions such as acne scars, swelling, the appearance of rosacea, and the elimination of bacteria that can contribute to acne flare-ups.

The Helichrysum I use is organic, and it is the only known therapeutic oil that contains diketones (regenerative compounds that promote youthful skin). It is one of the most precious and expensive oils due to its delightful fragrance and its ability to repair dryness and transform the complexion and the skin’s overall appearance. I love this immortal flower because when I use it on my face or body, I feel like it regenerates and nourishes my skin at the cellular level.”


“BOTOX-LIKE” TIGHTENING ACTIVES


SUMMER SNOWFLAKE

The bulb of the summer snowflake plant (also known as leucojum aestivum bulb extract) was recently patented in Australia as the first to bloom after the snow melts, which explains its name. Many plants go into “sleep mode” in winter, and the summer snowflake is one of the plants tested for slowing cell proliferation in the human body.

The extract acts by telling our cells to slow down, go dormant, and hibernate to help delay the aging process. It therefore gives us the power to naturally freeze our expression lines. Just as botox is a neurotoxin, summer snowflake acts similarly on the skin and facial muscles by blocking muscle contraction and reducing movement.

RESULTS IN 28 DAYS

30% reduction in the number of micro-lines. 15% reduction in the number of medium wrinkles

CALCIUM K

Calcium K is actually calcium ketogluconate, a natural molecule patented in France, which comes in the form of a pure powder and is used in many anti-aging products. With regular use, Calcium K will re-volumize your face, your cheekbones will be more defined, and your face will appear younger. It is an ultra-effective ingredient strongly supported by clinical and scientific studies showing convincing results, without the potential side effects of a traditional filler.

The main strength of Calcium K lies in its ability to tone and smooth wrinkles and fine lines from the inside out. Calcium K plays an important role in delaying the aging process by acting in the dermis, which is the middle and thickest layer of our skin, responsible for the production of elastin and hyaluronic acid. Calcium K helps your skin produce more hyaluronic acid, which is a natural filler, and synthesize elastin by naturally stimulating the skin. That is why it is so effective.

RESULTS IN 28 DAYS

Lifts the skin by 27%.

THE BEST ANTI-AGING DIETARY SUPPLEMENTS


RESVERATROL: THE ANTIOXIDANT SHIELD

Naturally present in grapes, berries, blackberries, and red wine, resveratrol is a powerful polyphenol that has been the subject of numerous scientific studies for its exceptional anti-aging properties. This super-antioxidant protects your cells from premature aging by neutralizing the free radicals responsible for oxidative stress. It effectively fights cell oxidation, a process that accelerates skin aging and the appearance of wrinkles. Resveratrol also improves blood circulation, which enables better oxygenation of skin tissues and a brighter, more even complexion. By stimulating collagen production and protecting elastin fibers from degradation, resveratrol helps maintain skin firmness and elasticity. It also has anti-inflammatory properties that soothe redness and irritation, making it a valuable ally for healthy, protected, and visibly younger-looking skin.

NMN: THE SECRET OF LONGEVITY

NMN (nicotinamide mononucleotide) is a revolutionary compound currently the subject of intense scientific research in the field of longevity and anti-aging. This direct precursor actively supports the production of NAD+ (nicotinamide adenine dinucleotide), an absolutely essential coenzyme molecule for maintaining optimal cellular function, energy production, and DNA repair. As we age, our NAD+ levels naturally decline, which contributes to the decline of our metabolic functions and the visible aging of the skin. NMN is recognized for its remarkable potential effects on cellular longevity, effectively slowing aging at the molecular level and significantly boosting vitality and overall energy. By restoring NAD+ levels, NMN helps improve energy metabolism, strengthen mitochondrial function, and activate sirtuins, anti-aging proteins that play a crucial role in cellular repair. For the skin, this translates into better regeneration, reduced signs of fatigue, a more radiant complexion, and visible improvement in skin texture. Today, NMN represents one of the most promising advances in scientifically validated anti-aging supplementation.

CHAGA: THE ADAPTOGENIC MUSHROOM THAT SLOWS TIME

Chaga is a rare and precious adaptogenic mushroom recognized worldwide for its exceptional anti-aging properties and extraordinary cellular protection power. Nicknamed “the king of mushrooms” or “the diamond of the forest,” chaga is extraordinarily rich in antioxidants, displaying one of the highest ORAC scores (antioxidant capacity) among all known superfoods. It notably contains impressive amounts of superoxide dismutase (SOD), a powerful anti-aging enzyme that helps effectively neutralize free radicals and protect cells from oxidative damage responsible for premature aging. In addition to its remarkable antioxidant properties, chaga contains beta-glucans and polyphenols that support cell regeneration and slow the aging process at the skin level. It helps visibly reduce signs of aging by protecting collagen and elastin from degradation, which maintains skin firmness and elasticity. Chaga also reduces chronic inflammation, a key factor in accelerated aging, and significantly improves overall skin health by promoting an even, luminous, and visibly rejuvenated complexion. By stimulating cellular repair from within, chaga helps preserve youthful skin over the long term.

SPERMIDINE: THE KEY TO CELLULAR REGENERATION

Spermidine is a fascinating natural polyamine found in foods such as fermented soybeans (natto), wheat germ, mushrooms, and certain aged cheeses, and it is attracting growing scientific interest for its remarkable anti-aging properties. This bioactive compound powerfully helps activate autophagy, a fundamental process of cellular cleaning and recycling that could be described as the “internal detoxification system” of our cells. Autophagy allows cells to eliminate damaged proteins, defective organelles, and metabolic waste that accumulate with age and accelerate aging. Spermidine actively promotes the deep regeneration of skin cells and effectively prevents premature cellular aging by maintaining optimal cellular functions. By stimulating this natural renewal process, it allows you to maintain a fresh, radiant, revitalized complexion over time, along with visibly more supple, plump, and resilient skin. Recent studies have also shown that spermidine helps extend cellular lifespan, improve collagen production, and reduce the appearance of fine lines and wrinkles. Taken regularly as a dietary supplement, spermidine represents an innovative anti-aging strategy that acts at the very core of the cellular aging process.

SEA MOSS: A NOURISHING ANTI-AGING TREATMENT

Sea moss, also known as Chondrus crispus, is an exceptional marine algae extraordinarily rich in powerful antioxidants, essential minerals (including iodine, zinc, magnesium, and calcium), and vitamins (A, C, E, K, and B) that help nourish the skin deeply and holistically. This marine superfood actively stimulates the production of collagen, the fundamental structural protein that maintains the skin’s firmness, elasticity, and youthfulness. Thanks to its high content of natural mucilage and amino acids, sea moss intensely hydrates the deeper layers of the epidermis while forming an invisible protective film on the skin’s surface. It effectively protects against free radicals and oxidative stress responsible for premature aging, while significantly strengthening the skin barrier and its natural protective function. This precious algae also helps soothe inflammation, improve skin texture, and reduce the appearance of fine lines and imperfections. With regular use, sea moss helps achieve visibly smoother, plumper, brighter skin that glows with health, while slowing the visible signs of skin aging.

SHILAJIT RESIN: THE ENERGY OF THE EARTH

Used for millennia in traditional Ayurvedic medicine, where it is considered a “destroyer of weakness,” Shilajit resin is a rare and precious organic mineral substance that seeps from the rocks of the high Himalayas. This powerful natural adaptogen is extraordinarily rich in more than 85 bioavailable ionic minerals and fulvic acids, unique organic compounds that act as nutritional carriers at the cellular level. Shilajit powerfully helps revitalize cells deeply by optimizing their energy metabolism, improve physical and mental endurance, and effectively slow the visible effects of skin and systemic aging. It works by actively neutralizing toxins accumulated in the body and revitalizing the essential cellular functions that decline with age. The fulvic acids contained in Shilajit also facilitate nutrient absorption, improve collagen production, and strengthen tissue regeneration. This sacred resin helps restore the skin’s vitality, improve its elasticity, reduce the appearance of wrinkles, and bring back a natural glow and renewed radiance. Taken regularly, Shilajit represents a true elixir of youth that works both from within and on outward appearance.

HE SHOU WU: THE ANTI-AGING ADAPTOGENIC PLANT

He Shou Wu (Polygonum multiflorum), whose poetic name literally means “Mr. He’s black hair” in reference to a Chinese legend, is a revered adaptogenic plant used for more than a thousand years in traditional Chinese medicine for its remarkable anti-aging and regenerative properties. This precious root is extraordinarily rich in powerful antioxidants, stilbenes, lecithin, and unique bioactive compounds that actively support cellular health and longevity at the deepest level. It is particularly renowned in Eastern tradition for its spectacular beneficial effects on overall longevity, energetic vitality, the prevention of premature graying, and radiant hair health, which are considered a direct reflection of inner youth. He Shou Wu powerfully helps tone the liver and kidney functions, two essential organs in Chinese medicine for maintaining youth and vital energy (“Jing”). It significantly improves blood circulation, which promotes better oxygenation of skin tissues, a radiant complexion, and a visible reduction in signs of fatigue. This adaptogenic plant also strengthens the immune system and the body’s natural defenses against stress and aggressions that accelerate aging. He Shou Wu is traditionally used to effectively prevent premature aging both at the skin and hair level, and to sustainably maintain a youthful, energetic, radiant appearance full of vitality. Taken regularly, it represents a true longevity tonic that nourishes the body from within.

GREEN POWDERS: “GREEN” BLENDS

Green powders are superfoods rich in essential nutrients for skin health and beauty. They contain an abundance of vitamins, minerals, antioxidants, and chlorophyll, which help detoxify the body, reduce inflammation, and protect cells against oxidative damage. Regular consumption of green powders can improve skin health, promote cell regeneration, and slow the signs of aging. These powders can easily be added to smoothies, juices, or meals for a daily boost of vitality and youthfulness.

FAQ - FREQUENTLY ASKED QUESTIONS ABOUT ANTI-AGING INGREDIENTS


Can several anti-aging actives be combined?

Yes. It is even recommended to combine actives for optimal effectiveness. For example: an immortelle serum in the morning + a botox-like active at night + collagen as a supplement. Simply avoid layering too many products in a single application.

Are botox-like actives as effective as botox?

Natural botox-like actives offer a gentle alternative without injections. Their action is progressive and less intense than medical botox, but they work in a similar way by relaxing the facial muscles. Visible results appear after 4 to 8 weeks of regular use.

At what age should you start anti-aging actives?

Prevention starts as early as age 25 with antioxidants (immortelle, vitamin C) and daily SPF. More powerful actives (botox-like, retinol) can be introduced around ages 30 to 35. Dietary supplements can be taken from age 25 to 30 onward.

Are supplements really necessary?

They are not mandatory but are highly recommended for a complete anti-aging approach. Topical actives work on the surface, while supplements (collagen, NMN, chaga) nourish the skin from within. The combined IN & OUT action gives the best results.

How long does it take to see results?

It depends on the active used:

  • Hydration (tremella): immediate to 1 week
  • Radiance (immortelle, green powders): 2 to 3 weeks
  • Firming (horsetail, collagen): 4 to 6 weeks
  • Wrinkles (botox-like actives): 4 to 8 weeks
  • Deep regeneration (NMN, spermidine): 8 to 12 weeks

Nature offers an extraordinary palette of anti-aging actives, from topical botanical ingredients to natural alternatives to botox, including powerful nutrients that work from within. Whether you are looking to prevent the signs of aging with horsetail and immortelle, correct expression lines with botox-like actives, or regenerate deeply with supplements like NMN and chaga, there is a natural solution suited to your needs.

The combined IN & OUT approach remains the most effective strategy for visible and lasting results. Topical actives work on the surface and in the dermis, while supplements nourish from within for optimal synergistic effect. The secret to youthful skin? Consistency and patience — natural actives need 4 to 8 weeks to reveal their full effects.

Discover our selection of products formulated with these exceptional actives and create your personalized anti-aging routine.